Abstract:Inhaled corticosteroids (ICS) are commonly prescribed to manage asthma and chronic obstructive pulmonary disease (COPD) due to their local anti-inflammatory effects in the airways. However, prolonged or high-dose ICS use…
has been associated with systemic adverse effects, including decreased bone mineral density (BMD) and increased risk of osteoporosis. This review aimed to examine the association between ICS use and the risk of osteoporosis or fractures, and to identify modifying factors such as dose, duration, patient age, sex, and type of corticosteroid used. Literature review was conducted using databases including PubMed, Scopus, and Web of Science. Articles were selected using specific inclusion and exclusion criteria. The review focused on original studies published up to March 2025, resulting in 28 relevant articles, of which 6–8 high-quality studies were analyzed in depth. Most studies demonstrated that long-term or high-dose ICS use is associated with decreased BMD and increased risk of fractures, especially in elderly COPD patients. The greatest risk was linked to fluticasone and budesonide at doses ≥500 µg/day. Some studies found neutral or even protective effects in specific subgroups, indicating population-dependent variability. Meta-analyses revealed conflicting results due to heterogeneity in populations and methodologies. High-dose and long-term ICS use may increase the risk of osteoporosis. Clinicians should consider individualized risk assessments and adopt strategies such as using the lowest effective dose, monitoring BMD, and providing calcium and vitamin D supplementation in at-risk populations.
Abstract:Home birth selection is a complex decision influenced by various factors. This study aimed to determine the relationship between knowledge and antenatal care (ANC) visits with the decision-making of home birth in the working…
king area of Mapaddegat Public Health Center, Mentawai Islands Regency. This research was a descriptive analytic study with a case-control design, conducted from February to May 2025, involving mothers who gave birth and were recorded in the maternal cohort data from January 2023 to December 2024. A systematic random sampling technique was applied, consisting of 21 respondents in the case group and 42 respondents in the control group. Data were analyzed using univariate and bivariate analysis with the chi-square statistical test. The univariate results showed that 74.6% had high knowledge, and 57.2% had more than four ANC visits. The bivariate analysis revealed a significant relationship between knowledge (p = 0.011; OR = 5.455) and the number of ANC visits (p = 0.015; OR = 4.462) with the decision to give birth at home. It can be concluded that there is a relationship between knowledge and the number of ANC visits with home birth decision-making. It is recommended for the Mapaddegat Public Health Center staff to strengthen health promotion regarding delivery in health facilities and develop innovations to increase the coverage of facility-based deliveries.
Abstract:This study examines the impact of ethical leadership, innovation adoption, and creativity on company performance within Indonesia's fast-fashion industry. As the industry faces increasing scrutiny regarding sustainability…
y and social responsibility, understanding the relationships between these organizational capabilities becomes crucial for competitive advantage. Using a quantitative methodology, this research employed saturated sampling of 87 managers from fast-fashion companies across major Indonesian cities including Jakarta, Bandung, Surabaya, and Medan. Data were analyzed using SmartPLS 4.0 through Partial Least Squares Structural Equation Modeling (PLS-SEM). The measurement model demonstrated strong reliability and validity, with all constructs exceeding recommended thresholds for Cronbach's Alpha (0.832-0.873), Composite Reliability (0.883-0.911), and Average Variance Extracted (0.603-0.671). Discriminant validity was confirmed through Fornell-Larcker criterion and HTMT ratios below 0.85. The findings reveal that ethical leadership, innovation adoption, and creativity function as complementary organizational resources that collectively enhance company performance rather than operating in isolation. These results provide empirical evidence for the synergistic effects of leadership behavior, technological orientation, and creative capacity in driving organizational success. The study contributes to management literature by demonstrating the integrated nature of these capabilities and offers practical guidance for fast-fashion companies seeking sustainable competitive advantage through ethical practices, systematic innovation, and creative organizational cultures.
Abstract:The integration of artificial intelligence (AI) in patent systems has emerged as a complex area in intellectual property law. This systematic literature review follows PRISMA 2020 guidelines to analyze AI implementation…
in patent systems, particularly within the Indonesian context. The study examines 11 key studies published between 2015-2025 through systematic searches across multiple academic databases. Results demonstrate that AI implementation has achieved significant improvements in operational efficiency, particularly in automated patent classification, prior art searching, and examination support systems. Approximately 190,000 AI patents were granted globally between 2000-2022, reflecting increasing technological importance. In Indonesia, AI implementation must align with Law No. 13 of 2016 on Patents as amended by Law No. 65 of 2024. The landmark Thaler v. Vidal case confirms AI cannot be an "inventor" but can serve as an assistive tool with significant human contribution. Key challenges include AI decision-making transparency and knowledge gaps among patent examiners.
Abstract:This study aims to analyze the implementation of the Hospital Management Information System (HMIS) and its impact on operational efficiency at XYZ Hospital in Pamekasan. In the digital era, hospitals are required to enhance…
nce service quality and operational efficiency through the utilization of information technology. HMIS is an innovation designed to integrate managerial and administrative processes within hospitals, including patient data recording, resource management, and other healthcare service procedures. This research adopts a descriptive qualitative approach with purposive sampling techniques, involving informants such as medical personnel, administrative staff, and hospital management who are directly involved in the use of HMIS.The results indicate that the implementation of HMIS has a positive impact on the hospital’s operational efficiency, including the acceleration of administrative processes, improved data accuracy, and easier coordination between work units. However, the implementation also faces several challenges, such as limited technological infrastructure, user resistance to change, and insufficient training for staff. These findings are supported by the HOT-Fit framework and Technology Acceptance Model (TAM), all of which emphasize the importance of technological readiness, human resource competence, and organizational commitment in ensuring the successful adoption of HMIS.
Abstract:The rapid proliferation of digital markets has intensified legal challenges surrounding the modification and resale of Creative Commons–licensed digital products in Indonesia. This study conducts a doctrinal analysis of…
f the Indonesian Copyright ActLaw No. 28 of 2014) in light of comparative jurisprudence from Japan, Taiwan, and the United States, elucidating how civil-law and common-law systems treat CC licenses. It examines recurring issues ambiguities in “derivative works,” conflicts between non-commercial and commercial exploitation clauses, and failures to observe attribution requirements through practical case studies of software, e-books, music, and video tutorials. Drawing on Satjipto Rahardjo’s progressive legal theory, the research argues for a functional, transformative approach that aligns domestic copyright doctrine with globally harmonized open-licensing principles and substantive justice. The analysis reveals that, under Indonesian law, permissibility hinges on strict adherence to each license’s specific terms; however, current regulations lack clarity, generating legal uncertainty for both creators and users. To address these gaps, the study proposes interpretative guidelines and legislative reforms that (1) define “derivative works” in accord with CC International’s porting model, (2) reconcile non-commercial provisions with legitimate digital markets, and (3) institutionalize attribution standards. Such measures would safeguard creators’ moral and economic rights while fostering equitable digital access and innovation, thereby enhancing Indonesia’s knowledge economy.
Abstract:This study examines the legal certainty of financing for Indonesia's Desa Merah Putih Cooperative (KDMP) initiative, analyzing the institutional tension between cooperative independence and state intervention. Rooted in…
the constitutional mandate for cooperatives as a cornerstone of the Indonesian economy, the KDMP program aims to establish 80,000 village-level cooperatives through state-facilitated credit lines and technical assistance. However, this top-down model raises concerns about undermining cooperative autonomy enshrined in Law No. 25/1992 and the principle of subsidiarity. Employing a normative juridical research design, this study draws on secondary data from legal literature and primary legal materials to systematically examine relevant norms and doctrines. Findings reveal a tenuous alignment between state financing mechanisms and cooperative autonomy, primarily due to the proposed reliance on state-owned bank credit lines rather than direct state budget grants, leading to legal ambiguity regarding accountability and oversight. The potential for mass loan defaults and the contentious use of Village Funds as collateral further complicate legal certainty and risk hidden liabilities. Comparative insights from India's Amul cooperative and the Philippines' barangay cooperatives illustrate successful models where government acts as a facilitator without impinging on cooperative self-governance or member control. This study advocates for a recalibrated regulatory approach featuring transparent oversight, proportional supervision, and participatory decision-making to reconcile developmental imperatives with cooperative principles, ultimately enhancing legal certainty and ensuring that state-supported cooperatives remain genuinely member-driven enterprises.
Abstract:This study aims to analyze the role of core competency strategies in human resources (HR) in improving company performance, with a case study at PT Waskita Beton Precast Tbk. The research focuses on three main aspects: identifying…
dentifying and analyzing the core competencies required in HR, strategies for managing core competencies in HR, and analyzing the relationship between core competencies in HR and company performance. The research method used is a descriptive qualitative approach with data collection techniques through in-depth interviews and direct observation. The research results indicate that the development of core HR competencies, such as leadership, technological mastery, and results orientation, plays a significant role in improving company performance and operational efficiency. Management strategies encompassing continuous training, performance evaluation systems, and strengthening a collaborative work culture are key to reinforcing core HR competencies. The findings also indicate a strong correlation between effective management of core HR competencies and overall improvements in company performance, which contributes to achieving long-term competitive advantage.
Abstract:Kawasan Pesisir Ciku Nyinyi tepatnya berada pada Desa Sidodadi, Kabupaten Pesawaran terdapat potensi ekowisata yang telah lama dikembangkan dan sempat menjadi tujuan wisata yang populer. Namun karena semakin lama ketertarikan…
rikan masyarakat pada ekowisata kawasan Mangrove menurun, serta pemanfaatan hutan Mangrove yang keliru membuat kawasan Mangrove semakin lama terbengkalai. Upaya yang dapat dilakukan salah satunya adalah memberi pemahaman kepada masyarakat sekitar akan fungsi hutan Mangrove bagi kawasan pesisir. Peningkatan pengetahuan dan pemahaman masyarakat dalam konservasi untuk menjaga kelestarian hutan Mangrove pada kegiatan ini sebesar 91 %. Setelah dilakukan konservasi Mangrove dengan pendekatan pengabdian kepada masyarakat, pemahaman masyarakat akan pentingnya hutan Mangrove meningkat, secara tidak langsung kesadaran untuk menjaga keseimbangan ekosistem hutan Mangrove juga akan meningkat.
Abstract:This study highlights the urgent need to instill an understanding of religious moderation among church congregations in Indonesia’s pluralistic society, as a means to reduce religious tensions and extremism. Although the…
he Indonesian government has promoted the concept of religious moderation, its implementation within church communities remains underexplored. This research aims to identify effective strategies for fostering a moderate and inclusive understanding of religious moderation within Indonesian church congregations. A qualitative methodology was employed using a literature review approach based on relevant scholarly sources. Findings indicate that foundational strategies involve strengthening theological understanding of religious moderation from a Christian perspective, emphasizing core teachings such as love as the greatest commandment, Christian hospitality as practical application, and the theological principle of mutual acceptance (Romans 15:7). Furthermore, the study underscores the vital role of churches in this process through inclusive religious education, improved moderate religious literacy, responsible use of social media, engagement in interfaith dialogue, and systematic training programs. Cultivating a moderate and inclusive attitude requires nurturing humility, reinforcing national commitment in line with Pancasila, embracing diversity, rejecting extremism, and actualizing these values in daily life. To overcome challenges, the study recommends effective socialization, enhanced religious literacy, wise media engagement, collaboration with various stakeholders, exemplary leadership, and continuous program evaluation. The study concludes that religious moderation is an essential contribution of the church to national unity, conflict prevention, the upholding of national values, interfaith harmony, and the strengthening of national identity.