Abstract:Obesity is a condition of abnormal or excessive fat accumulation which can be a risk factor for dyslipidemia. Uncontrolled dyslipidemia can directly cause endothelial dysfunction by increasing the production of free radicals,…
cals, causing Low Density Lipoprotein (LDL) oxidation and stimulating the release of inflammatory factors that can cause inflammation. Neutrophils and macrophages are the first leucocytes to appear in the early response to inflammation, so the neutrophil-lymphocyte ratio can be useful for evaluating the prognosis of inflammation as an early detector and as a marker of inflammation that can be detected simply and efficiently. This study aims to determine the correlation between Neutrophil-Lymphocyte Ratio (NLR) and Lipid Profile in adult patients with obesity in Prodia Tangerang Clinical laboratory. This study is an analytical study with a cross-sectional approach and used purposive sampling technique. The research sample data was taken from secondary data from patient medical records. The p-value obtained using Rank Spearman correlation from the comparation of neutrophil-lymphocyte ratio with each lipid profile value is total cholesterol (p=0.003), LDL cholesterol (p=0.013), High Density Lipoprotein (HDL) cholesterol (p=0.375) and tryglicerides (p=0.316). This study found a relationship between the neutrophil-lymphocyte ratio with total cholesterol dan LDL cholesterol, but there was no relationship between the neutrophil-lymphocyte ratio with HDL cholesterol and tryglicerides in obese adult patient in Prodia Tangerang Clinical Laboratory.
Abstract:Fever is the most common disease in children. Fever in children can be found in various conditions such as infection, inflammation, or other unknown causes. One of the laboratory tests that can be used is the hs-CRP and…
erythrocyte sedimentation rate examination. The purpose of this study was to determine the relationship between hs-CRP levels and erythrocyte sedimentation rate in pediatric febrile patients. The research method was observational with a cross-sectional method using secondary data of 62 samples. Data analysis used the Spearman's rho test. The results of the study showed that most of the pediatric patients who experienced fever were male (59.7%), and the age of the child was 5 years (21%). In pediatric patients with fever, the average hs-CRP level was 19.34 mg/l, and the erythrocyte sedimentation rate was 32.73 mm/hour. The results of the correlation test using the Spearman's rho test method obtained p = 0.001 with r = 0.575, so it can be concluded that there is a moderate and positive relationship between hs-CRP levels and erythrocyte sedimentation rate in pediatric patients with fever.
Abstract:Background: Gout arthritis is a degenerative disease commonly experienced by the elderly due to elevated uric acid levels in the blood. One safe non-pharmacological treatment alternative is the use of herbal remedies such…
h as soursop leaves (Annona muricata L), which contain active compounds like flavonoids and alkaloids that may reduce uric acid levels. Objective: To describe the effect of boiled soursop leaf water on reducing uric acid levels in elderly patients with gout arthritis in Karangjambu Village, Karangjambu Subdistrict, Purbalingga Regency. Method: This study employed a case study method. Subjects were given an intervention of 200 ml of boiled soursop leaf water daily (100 ml in the morning and 100 ml in the evening) for seven consecutive days. Uric acid levels were measured before and after the intervention. Results: After seven days of soursop leaf water administration, uric acid levels decreased from an average of 8.7–9.0 mg/dl to 5.5–5.8 mg/dl. This suggests that the active compounds in soursop leaves are effective in inhibiting xanthine oxidase and promoting uric acid excretion through urine. Conclusion: Boiled soursop leaf water is effective in lowering uric acid levels in elderly patients with gout arthritis and can serve as a safe and practical complementary non-pharmacological therapy within the community.
Abstract:Urine alcohol testing plays a vital role in detecting alcohol consumption for clinical and forensic purposes, yet its results may be influenced by pre-analytical factors such as the delay between sample collection and laboratory…
boratory analysis. This study aimed to evaluate the effect of delay time before urine examination on alcohol concentration. An experimental One-Shot Case Study design was conducted involving 44 participants in Denpasar who had consumed alcohol. Alcohol concentration was measured immediately, after a 2-hour delay, and after a 4-hour delay using the Alcohol Urine Rapid Test Dipstick Allchek, and the data were analyzed using the Kruskal-Wallis test. The findings showed that average urine alcohol levels increased numerically after a 2- and 4-hour delay compared to immediate testing; however, this change was not statistically significant (p=0.131). These results confirm that delaying urine alcohol examination up to 4 hours does not significantly alter detectable alcohol concentrations, although prompt testing is still recommended to ensure result accuracy and minimize the risk of false positives. This study provides important insights for the development of standard operating procedures regarding urine alcohol analysis in laboratory practice.
Abstract:Exposure to X-ray radiation in conventional radiology procedures can pose a health risk, especially for accompanying caregivers of pediatric patients who only bear the risk without gaining any benefit. This study aims to…
determine the estimated equivalent dose received by accompanying caregivers of pediatric patients and the safest points during conventional radiology examinations. The method used in this research is a field survey, involving the measurement of equivalent radiation doses inside and outside the examination room using a personal dosimeter, as well as measuring the radiation dose rate at 6 points using a surveymeter. The data was processed to obtain the highest and lowest values, as well as the percentage of equivalent dose obtained compared to the established Dose Limit Value (DLV). The results showed that the highest radiation dose received by accompanying caregivers inside the examination room reached 13,46 µSv, with a percentage of 0,27% relative to the DLV, while the lowest dose recorded was 1,12 µSv, with a percentage of 0,0224% relative to the DLV. Analysis of the radiation dose rate distribution revealed that the greater the distance of the measurement point from the radiation source (tube), the smaller the dose received. In conclusion, the radiation dose received by accompanying caregivers is still below the Dose Limit Value (DLV) for caregivers, which is 5.000 µSv. However, to minimize stochastic effects, the implementation of additional protective measures, such as the use of lead aprons and selecting safer locations within the examination room, is highly recommended. These findings are expected to serve as a guide in enhancing the safety of accompanying caregivers of pediatric patients in conventional radiology units.
Abstract:Marriage involving pregnant women outside wedlock remains a critical socio-cultural and legal phenomenon in Indonesia, particularly in North Halmahera where family honor, religious authority, and customary law strongly influence…
nfluence communal life. This study aimed to explore how such marriages are understood, legitimized, and practiced by families, community leaders, and legal institutions. Using a qualitative case study approach, data were collected through in-depth interviews with religious leaders, adat leaders, government officials, parents, and young women, complemented by participant observation and document analysis, and analyzed with an interactive model of reduction, display, and conclusion drawing. The findings reveal that marriage is primarily arranged to safeguard family honor, with communities regarding it as the only socially acceptable corrective measure, while religious leaders across traditions adopt pragmatic interpretations, invoking public interest or redemption to justify the practice, and customary rituals together with state dispensations further reinforce its legitimacy. Although marriage resolves immediate stigma and reintegrates families socially, it simultaneously generates long-term vulnerabilities, including interrupted education, economic dependence, marital instability, psychological stress, and increased maternal and neonatal health risks. This study contributes to the sociology of law and religion by demonstrating how socio-cultural confinement, Islamic legal pluralism, and adat practices converge in eastern Indonesia, while underscoring the urgent need for holistic interventions that integrate sexuality education, family communication, religious engagement, and legal reform to protect women and children more effectively.
Abstract:Diabetes Mellitus (DM) is a disease caused by pancreatic failure in performing its function of producing insulin. A lack of insulin will lead to an increase in blood glucose levels, also known as hyperglycemia. Hemoglobin…
n A1c and microalbuminuria are screening examinations used to detect the early onset of diabetic nephropathy. Diabetic nephropathy is defined as a clinical syndrome in diabetes mellitus patients characterized by persistent albuminuria, an irreversible decrease in glomerular filtration rate, and increased arterial blood pressure. The purpose of this study is to determine the relationship between Hemoglobin A1c and microalbuminuria in diabetes mellitus patients at Prodia Sunter. The research method used is quantitative analytic with a cross-sectional approach. The data collected were secondary data from the period of January–July 2024 with a total of 60 samples. Sampling was conducted using purposive sampling and met the inclusion criteria, namely patients over 60 years of age, Hemoglobin A1c value ≥7, diagnosed with diabetes mellitus, no history of thalassemia, and who had undergone Hemoglobin A1c and microalbuminuria examinations. The results of this study show a significant unidirectional positive relationship with a very strong correlation between Hemoglobin A1c levels and microalbuminuria in diabetes mellitus patients, with sig (2-tailed) = 0.000 and correlation coefficient value = 0.892. The relationship between Hemoglobin A1c levels and microalbuminuria is unidirectional positive, meaning that the higher the Hemoglobin A1c levels, the higher the microalbuminuria levels.
Abstract:Green betel leaves contain compounds that can treat vaginal discharge, especially those caused by bacteria. To determine the effect of green betel leaf extract on the growth of Bacteroides in vaginal secretion cultures,…
this study used a quantitative experimental method, where vaginal secretion samples were taken from the subjects and then tested quantitatively. There were two data collection techniques used in this study: using a questionnaire and testing vaginal secretion samples with green betel leaf extract. The test for using was diffusion (paper disc) for the antibacterial test. The media used was MHA. The positive control used was a blank disc, the extract concentration series used were 20%, 25% and 30%. The diameter of the inhibition zone was observed and then analyzed. The results of the t-test analysis showed that the significance value was 0.00 <0.05, so H0 was rejected Ha was accepted or it could be concluded that there was a difference in the effect of giving green betel leaf extract on the growth of Bacteroides in vaginal secretion culture. Antibacterial activity test of green betel leaves (Piper betle L) against Bacteroides bacteria that cause Bacterial Vaginosis, namely resistant at a concentration of 20%, intermediate at a concentration of 25% and sensitive at a concentration of 30%. Green betel leaf extract (Piper betle L) has inhibitory power against Bacteroides bacteria that cause Bacterial Vaginosis. Can increase the concentration series of methanol extract of green betel leaves, find the minimum bactericidal concentration (MBC) and the maximum inhibitory concentration (MIC) of green betel leaf extract against Bacteroides bacteria that cause Bacterial Vaginosis
Abstract:The challenges of modern education demand not only academic achievement but also the cultivation of students’ noble character. In this context, the role of principals in Integrated Islamic Senior High Schools (SMA IT) becomes…
becomes highly strategic. This study aims to analyze and describe the role and influence of principals’ Islamic integrative leadership on improving the performance of educational staff within SMA IT. A qualitative approach with a phenomenological method was employed. Data were obtained through in-depth interviews with principals and educational staff as well as participant observation. Analysis was conducted interactively through data reduction, presentation, and conclusion drawing. The findings show that Islamic integrative leadership which combines modern leadership models such as transformational, instructional, democratic, servant, and distributive leadership with Islamic values such as exemplary conduct (uswah hasanah), consultation (syura), trustworthiness (amanah), justice, and a clear vision significantly enhances the performance of educational staff. The integration of these values creates a work culture imbued with a spirit of worship, collaboration, and quality orientation. Educational staff become more motivated, loyal, and productive as they view their work as part of worship. This study concludes that Islamic integrative leadership is not merely a leadership style but an effective organizational culture foundation at SMA IT. Its implementation has been proven to empower educational staff, improve their performance, and support the achievement of sustainable Islamic educational goals. This leadership model is recommended for broader development in Islamic educational institutions.
Abstract:This thesis discusses the implementation of the Inside Outside Circle (IOC) learning model to improve the learning activities of Grade VII-1 students. In the initial condition, students showed low learning activity, as reflected…
eflected in their behavior during lessons. The purpose of this study is to analyze the implementation of the Inside Outside Circle (IOC) learning model in enhancing the learning activities of Grade VII students at SMP Negeri 1 Noling. This research employed Classroom Action Research (CAR) using the Spencer Kagan model. The study was conducted in two cycles involving 21 students as research subjects. Data collection techniques included observation, teacher observation sheets, student observation sheets, and student activity sheets, which were then analyzed both quantitatively and qualitatively. The findings revealed an increase in the average student learning activity score from 43.40% in Cycle I to 92.15% in Cycle II. This study demonstrates that the implementation of the Inside Outside Circle (IOC) learning model is effective in improving the learning activities of Grade VII students at SMP Negeri 1 Noling.