Abstract:The emergence of the COVID-19 pandemic in 2019 has had an impact on all aspects of life, particularly global health. Indonesia is one of the affected countries. The Indonesian government has responded to the conditions of…
f this pandemic, one of which is by imposing access restrictions to prevent the pandemic from spreading. This policy indirectly affects the community's activities, including the utilization of existing healthcare services. Meanwhile, available data show that one of the major issues that the Indonesian state is still dealing with is its status as the third country with the greatest number of TB (Tuberculosis) cases in the world, with some of the TB cases being classified as Drug-Resistant Tuberculosis (DR-TB).
Abstract:Obesity is a condition of abnormal or excessive fat accumulation which can be a risk factor for dyslipidemia. Uncontrolled dyslipidemia can directly cause endothelial dysfunction by increasing the production of free radicals,…
cals, causing Low Density Lipoprotein (LDL) oxidation and stimulating the release of inflammatory factors that can cause inflammation. Neutrophils and macrophages are the first leucocytes to appear in the early response to inflammation, so the neutrophil-lymphocyte ratio can be useful for evaluating the prognosis of inflammation as an early detector and as a marker of inflammation that can be detected simply and efficiently. This study aims to determine the correlation between Neutrophil-Lymphocyte Ratio (NLR) and Lipid Profile in adult patients with obesity in Prodia Tangerang Clinical laboratory. This study is an analytical study with a cross-sectional approach and used purposive sampling technique. The research sample data was taken from secondary data from patient medical records. The p-value obtained using Rank Spearman correlation from the comparation of neutrophil-lymphocyte ratio with each lipid profile value is total cholesterol (p=0.003), LDL cholesterol (p=0.013), High Density Lipoprotein (HDL) cholesterol (p=0.375) and tryglicerides (p=0.316). This study found a relationship between the neutrophil-lymphocyte ratio with total cholesterol dan LDL cholesterol, but there was no relationship between the neutrophil-lymphocyte ratio with HDL cholesterol and tryglicerides in obese adult patient in Prodia Tangerang Clinical Laboratory.
Abstract:Urine alcohol testing plays a vital role in detecting alcohol consumption for clinical and forensic purposes, yet its results may be influenced by pre-analytical factors such as the delay between sample collection and laboratory…
boratory analysis. This study aimed to evaluate the effect of delay time before urine examination on alcohol concentration. An experimental One-Shot Case Study design was conducted involving 44 participants in Denpasar who had consumed alcohol. Alcohol concentration was measured immediately, after a 2-hour delay, and after a 4-hour delay using the Alcohol Urine Rapid Test Dipstick Allchek, and the data were analyzed using the Kruskal-Wallis test. The findings showed that average urine alcohol levels increased numerically after a 2- and 4-hour delay compared to immediate testing; however, this change was not statistically significant (p=0.131). These results confirm that delaying urine alcohol examination up to 4 hours does not significantly alter detectable alcohol concentrations, although prompt testing is still recommended to ensure result accuracy and minimize the risk of false positives. This study provides important insights for the development of standard operating procedures regarding urine alcohol analysis in laboratory practice.
Abstract:Diabetes Mellitus (DM) is a disease caused by pancreatic failure in performing its function of producing insulin. A lack of insulin will lead to an increase in blood glucose levels, also known as hyperglycemia. Hemoglobin…
n A1c and microalbuminuria are screening examinations used to detect the early onset of diabetic nephropathy. Diabetic nephropathy is defined as a clinical syndrome in diabetes mellitus patients characterized by persistent albuminuria, an irreversible decrease in glomerular filtration rate, and increased arterial blood pressure. The purpose of this study is to determine the relationship between Hemoglobin A1c and microalbuminuria in diabetes mellitus patients at Prodia Sunter. The research method used is quantitative analytic with a cross-sectional approach. The data collected were secondary data from the period of January–July 2024 with a total of 60 samples. Sampling was conducted using purposive sampling and met the inclusion criteria, namely patients over 60 years of age, Hemoglobin A1c value ≥7, diagnosed with diabetes mellitus, no history of thalassemia, and who had undergone Hemoglobin A1c and microalbuminuria examinations. The results of this study show a significant unidirectional positive relationship with a very strong correlation between Hemoglobin A1c levels and microalbuminuria in diabetes mellitus patients, with sig (2-tailed) = 0.000 and correlation coefficient value = 0.892. The relationship between Hemoglobin A1c levels and microalbuminuria is unidirectional positive, meaning that the higher the Hemoglobin A1c levels, the higher the microalbuminuria levels.
Abstract:Dengue Hemorrhagic Fever (DHF) is a disease caused by the Dengue virus transmitted to humans through the bite of the Aedes aegypti and Aedes albocpitus mosquitoes. One of the laboratory tests that can help diagnose Dengue…
e fever includes Dengue IgM and IgG Antigens and hematology tests. The number of lymphocytes plays a role in the body's immune system and is one of the parameters found in hematology tests. This study aims to determine the relationship between Dengue IgM and IgG antibodies and the number of lymphocytes in patients suspected of having Dengue fever at the Prodia Sunter Clinical Laboratory for the period 2021-2024. The research method is observational with cross-sectional using secondary data of 104 samples. Data analysis uses Spearman rank. The results of the study showed that most of the suspected Dengue fever patients were male, 56 patients (53.8%) with the highest age at 19-59 years as many as 53 patients (51.0%) and the duration of fever was mostly experienced on the 3rd day of fever 29 patients (27.9%). The results of the Dengue antigen IgM examination in suspected Dengue fever patients were negative for 89 patients (85.6%) and the Dengue antigen IgG was negative for 64 patients (61.5%). The number of lymphocytes was within normal limits for 44 patients (42.3%). The results of the IgM correlation test obtained p = 0.005 with r 0.271, so the hypothesis was accepted, it can be concluded that there is a weak correlation between Dengue IgM antibodies and the number of lymphocytes and the results of the IgG correlation test obtained p = 0.043 with r 0.198, so the hypothesis was accepted, it can be concluded that there is a weak correlation between Dengue IgG antibodies and the number of lymphocytes in suspected Dengue fever patients.
Abstract:Inhaled corticosteroids (ICS) are commonly prescribed to manage asthma and chronic obstructive pulmonary disease (COPD) due to their local anti-inflammatory effects in the airways. However, prolonged or high-dose ICS use…
has been associated with systemic adverse effects, including decreased bone mineral density (BMD) and increased risk of osteoporosis. This review aimed to examine the association between ICS use and the risk of osteoporosis or fractures, and to identify modifying factors such as dose, duration, patient age, sex, and type of corticosteroid used. Literature review was conducted using databases including PubMed, Scopus, and Web of Science. Articles were selected using specific inclusion and exclusion criteria. The review focused on original studies published up to March 2025, resulting in 28 relevant articles, of which 6–8 high-quality studies were analyzed in depth. Most studies demonstrated that long-term or high-dose ICS use is associated with decreased BMD and increased risk of fractures, especially in elderly COPD patients. The greatest risk was linked to fluticasone and budesonide at doses ≥500 µg/day. Some studies found neutral or even protective effects in specific subgroups, indicating population-dependent variability. Meta-analyses revealed conflicting results due to heterogeneity in populations and methodologies. High-dose and long-term ICS use may increase the risk of osteoporosis. Clinicians should consider individualized risk assessments and adopt strategies such as using the lowest effective dose, monitoring BMD, and providing calcium and vitamin D supplementation in at-risk populations.
Abstract:Congenital hypothyroidism (CH) is an endocrine disorder that can cause developmental delays if not detected and treated early. Congenital Hypothyroidism Screening (CHS) aims to detect abnormal levels of Thyroid Stimulating…
ng Hormone (TSH) in newborns before clinical symptoms appear. The timing of blood sample collection is a critical factor because TSH levels physiologically surge within the first 24 hours of life. This study aims to determine the accuracy of TSH sampling time in CH screening at Prima Medika General Hospital, Denpasar. A descriptive analytical method was used with a total sampling technique involving 105 neonates who underwent CHS from October to December 2024. Secondary data were obtained from laboratory request forms and the Laboratory Information System (LIS). Results showed that 92.4% of samples were collected on the second day of life, which aligns with the ideal window of 48–72 hours, and only 1.9% of neonates had elevated TSH levels. The study concludes that most sample collections met the recommended timing, contributing to valid results and effective CHS implementation. Timely sampling plays a vital role in early CH detection and reflects the overall quality of neonatal laboratory services.
Abstract:People really need health services provided by hospitals, health homes and clinics. When registering for health services, each enrolling member will have his or her own medical history which must be seen at a medical clinic…
nic or health office. Hospitals must have comprehensive patient data in order to provide health services effectively. Documents regarding patient identity, examinations, treatment, procedures and other services are included in the medical record. In a health facility, implementation takes the form of an administrative order. Characteristics of medical records (General Patients or BPJS). The aim of this research is to determine the completeness of electronic medical resumes seen from fourth aspects, namely, completeness of identification, important reports, authentication and correct documentation . The method used in this research is quantitative analysis with a descriptive approach. The results of this research are that in the Identification component the percentage of completeness is 100% complete, in the Important Report component the percentage of completeness is 99%, in the Authentication component the percentage of completeness is 100%, and in the Correct Documentation component the percentage of completeness is 90%. Based on the results of research that has been carried out regarding completeness When filling out electronic medical resumes for patients in the Inpatients at RSU Dharma Yadnya, it can be concluded that there are still incompleteness in filling out inpatient electronic medical resumes and that the electronic medical resume components are filled in completely.
Abstract:One measure of service success is patient satisfaction; in the world of health, patient satisfaction indicates that the services provided have been delivered properly by health workers. The purpose of this study was to analyze…
nalyze the relationship between waiting time and outpatient satisfaction at Gunung Maria Tomohon Hospital. The method used in this research is quantitative research which is descriptive analytic using a cross-sectional study approach with a sample of 266 respondents (total sampling) with univariate and bivariate analysis. The results showed that based on the results of the chi-square test, a value of p = 0.001 (<α = 0.05) was obtained, indicating that there is a relationship between waiting time and outpatient satisfaction at Gunung Maria Tomohon Hospital. Based on the results of the analysis, it can be concluded that there is a relationship between waiting time and outpatient satisfaction at the Outpatient Polyclinic of Mount Maria Tomohon Hospital. As a suggestion for hospital leaders, especially for outpatient directors at Gunung Maria Tomohon Hospital, it is recommended to set health service standards, particularly for outpatients, to enhance their satisfaction.
Abstract:Sunnah cupping therapy (al-hijamah) is a popular Islamic healing method practiced globally. Despite its spiritual roots, it poses clinical risks, including infections, vasovagal shock, and procedural inconsistencies, often…
en due to non-sterile tools and untrained practitioners. This study aims to explore how Islamic ethical values—sincerity (ikhlas), trust (amanah), and halal compliance—can be integrated with clinical responsibilities such as sterilization protocols, informed consent, and therapist competency. A thematic qualitative literature review was conducted using Islamic jurisprudence, fatwas (DSN-MUI), WHO and Ministry of Health (Indonesia) guidelines from 2015–2025. Findings reveal that neglecting the maqashid sharia principle of hifzh an-nafs (protection of life) contradicts both Islamic ethics and medical safety. Sunnah cupping services rooted in both spiritual values and professional protocols are more trusted by Muslim patients and improve therapeutic legitimacy. This study highlights the urgent need for national SOPs, certified training, and the development of Islamic cupping clinics with integrated protocols. These clinics can serve as models of sharia-compliant, clinically responsible health services. The research offers practical recommendations for Islamic medical institutions and policy-makers in strengthening Islamic-based complementary therapies in modern healthcare systems.