Abstract:Background: Diabetes mellitus is a chronic metabolic disorder caused by high levels of physical activity, high sugar consumption, reduced insulin production, and impaired insulin response or other hormones that inhibit insulin…
nsulin action. Based on IDF data, the prevalence of diabetes mellitus in Indonesia in 2024 is estimated to reach 11.3% of the population (approximately 20.4 million people). In addition, the Ministry of Health shows that in 2023, cases of diabetes mellitus will reach 11.7% and are predicted to continue to increase. High blood glucose levels, if left untreated, can cause various complications such as heart disease, stroke, nerve damage, and wound infections that can lead to amputation. One non-pharmacological treatment that can be given is by giving boiled moringa leaves, because moringa leaves contain antioxidants such as flavonoids, vitamins A, C, and E which can lower blood glucose levels. Objective: To determine the effect of Moringa leaf decoction on reducing blood glucose levels in diabetes mellitus patients in Sikampuh Village, Kroya District, Cilacap Regency. Method: The method used was a qualitative descriptive method with a case study approach. Results: Based on the research results, administering Moringa leaf decoction to blood glucose levels in diabetes mellitus patients for 7 days was proven to be effective in lowering blood glucose levels. Conclusion: Administering Moringa leaf decoction to diabetes mellitus patients for 7 days can lower blood glucose levels.
Abstract:This study investigates the influence of gender, family economic background, and entrepreneurship education on the entrepreneurial interest of vocational high school students in Depok. Using a quantitative explanatory design,…
sign, data were collected from 123 students via structured questionnaires and analyzed through t-tests, F-tests, and multiple linear regression. The results show that all three variables positively affect entrepreneurial interest, with entrepreneurship education emerging as the strongest predictor (β = 0.641, p < 0.001), followed by family background (β = 0.239, p = 0.006) and gender (β = 0.228, p = 0.012). These findings indicate that students’ entrepreneurial intention is primarily shaped by formal entrepreneurship education, supported by family influence and gender-related differences in confidence and risk orientation. The study emphasizes the importance of practical entrepreneurship education and a supportive family environment in fostering entrepreneurial interest among vocational students, contributing to a sustainable youth entrepreneurship ecosystem.
Abstract:Background: Cardiovascular disease (CVD) continues to be the predominant cause of global mortality. Polypill techniques that integrate various cardiovascular drugs into a single formulation have emerged as a potential method…
thod for primary prevention, especially in intermediate-risk populations.
Objective: To systematically review and synthesize evidence regarding the efficacy and safety of polypill formulations (comprising antihypertensive medications, statins, with or without aspirin) in comparison to standard care or placebo for the primary prevention of major adverse cardiovascular events (MACE) in intermediate-risk populations.
Methods: We conducted systematic review and meta-analysis in accordance with PRISMA 2020 standards (Systematic Review Registration: PROSPERO CRD420251184718). Various databases (PubMed, Cochrane Library, ScienceDirect, Scopus) were examined for original research published from January 2015 to October 2024. Studies were eligible if they assessed polypill therapies in individuals aged 30 to 70 years with intermediate cardiovascular risk (10-20% 10-year risk), reported composite major adverse cardiovascular events (MACE) outcomes, and included a minimum follow-up of 6 months. Two independent reviewers conducted screening, data extraction, and risk of bias evaluation utilizing the Cochrane RoB 2.0 tool.
Results: Of the 161 records discovered, 4 randomized controlled studies (HOPE-3, TIPS-3, PolyIran, PolyPars) with 31,501 people fulfilled the inclusion criteria. Polypill therapies showed a substantial decrease in composite MACE relative to control groups (pooled HR 0.67 (95% CI 0.60-0.75, p<0.001). Individual trial hazard ratios varied from 0.50 (PolyPars) to 0.66 (PolyIran) and 0.79 (TIPS-3) with moderate heterogeneity (I²=35.2%, p=0.20). Polypills were generally well- tolerated, with a safety profile consistent with the individual components. Medication adherence was enhanced with the polypill in comparison to multiple-pill regimens.
Conclusions: Polypill techniques markedly reduce major adverse cardiovascular events (MACE) in intermediate-risk patients for primary cardiovascular prevention, achieving around a 33% relative risk reduction. The fixed-dose combination strategy provides benefits in compliance and ease of use. These findings hold significant implications for healthcare systems in low-to-
middle-income nations, such as Indonesia, where the burden of cardiovascular disease is substantial and access to long-term cardiovascular drugs is frequently hindered by cost and complexity.
Abstract:Abstract This study aims to analyze the effect of the implementation of immersive learning on student motivation and learning independence at Padangsidimpuan Public Elementary School 200306. The background of this research…
arch stems from the need to provide a learning process that is not only oriented towards final results, but also encourages students to understand the meaning of learning, think critically, and take responsibility for their learning process. The research method used was a quantitative approach with a quasi-experimental design. The study subjects included 50 fifth-grade students divided into an experimental group and a control group. Data collection instruments included a learning motivation questionnaire, a learning independence observation sheet, and documentation of learning outcomes. Data were analyzed using a t-test to determine significant differences between the two groups.
The results showed that the implementation of immersive learning had a positive and significant impact on increasing student motivation and learning independence. Students participating in immersive learning demonstrated greater enthusiasm, active question-asking, and the ability to manage assignments independently compared to those in the control group. These findings indicate that immersive learning strategies can be an effective alternative in developing reflective, independent, and problem-solving-oriented learners. Thus, the implementation of immersive learning in elementary schools needs to be continuously strengthened through teacher training, the development of teaching materials, and a learning culture that fosters students' ongoing curiosity.
Abstract:Background: Preschool-Aged children, aged 3–6 years, where the preschool period becomes a very fun time and get various new things. The weakness experienced by preschool children is that their immune system is weaker than…
han adults, which makes them more susceptible to infections, as well as the risk of falls and injuries, so they require medical treatment in the hospital. Childern who undergoing treatment at the Puskesmas can cause anxiety for them because they must leave their familiar, safe, loving, and enjoyable home environment. Hospitalization is a planned medical procedure that requires care and treatment but can trigger anxiety in children, both mentally and physically. Anxiety will cause children to become uncooperative and difficult to cooperate with health workers. During this process, children may face traumatic experiences that cause stress. One of the efforts to reduce the level of anxiety is by implementing play therapy, one of which is the coloring play therapy technique. Objective: This research describes the application of coloring play therapy on anxiety levels in preschool-aged children at Padamara Health Center. Methods: This research used a case study research design method. Results: This research indicate that before the intervention score was 25 (moderate anxiety) and after the intervention score was 9 (no anxiety). Conclusion: Coloring play therapy can reduce anxiety levels in preschool-aged children undergoing treatment at Padamara Health Center.
Abstract:Background: Anemia is a condition in which the level of red blood cells or hemoglobin in the body is below normal. In pregnant women, anemia can pose health risks to both the mother and the fetus. One of the non-pharmacological…
logical treatments that can be used is the administration of natural ingredients such as beetroot, which serves as an alternative due to its content of iron, folic acid, and vitamin C that can help increase hemoglobin levels. Objective: To provide an overview of the implementation of beetroot juice to increase hemoglobin levels in pregnant women with anemia. Methods: This study used a case study design involving one pregnant woman with anemia who met the inclusion criteria. The intervention consisted of administering 200 ml of beetroot juice per day for seven consecutive days. Evaluation was carried out by measuring hemoglobin levels before and after the intervention using the Easy Touch GCHb device. Results: The results showed that hemoglobin levels increased from 10.5 g/dL before the intervention to 11.8 g/dL after seven days, with an increase of 1.3 g/dL. Conclusion: Regular administration of beetroot juice is effective in increasing hemoglobin levels in pregnant women with anemia.
Abstract:Background: Elderly individuals are at high risk of experiencing degenerative diseases, one of which is gout arthritis, caused by the accumulation of monosodium urate crystals in the joints due to hyperuricemia. Non-pharmacological…
macological therapies such as bay leaf (Syzygium polyanthum), which contains flavonoids, tannins, and essential oils, are believed to naturally reduce uric acid levels. Objective: To determine the effect of bay leaf decoction on reducing uric acid levels in elderly patients with gout arthritis in Serang Village. Method: This research used a descriptive approach with a case study method. The subject was one elderly person with gout arthritis who was given an intervention in the form of bay leaf decoction twice a day for four days. Results: The uric acid level before the intervention was 8.2 mg/dL and after the intervention was 4.2 mg/dL. The reduction of 4 mg/dL indicates that the bay leaf decoction was effective in lowering uric acid levels. Conclusion: Bay leaf decoction affects the reduction of uric acid levels in elderly patients with gout arthritis and can be used as a safe, easy, and affordable nonpharmacological alternative therapy.
Abstract:Background: Hypertension is a common non-communicable health problem among the elderly and poses a risk of serious complications. Nonpharmacological therapy using tomato juice—which is rich in potassium and lycopene—has…
has the potential to naturally lower blood pressure. Objective: To observe the changes in blood pressure in elderly patients with hypertension following the administration of tomato juice. Method: A case study design involving one elderly respondent (78 years old) with mild hypertension. The intervention consisted of administering 200 ml of tomato juice every morning before meals for 7 consecutive days. Blood pressure was measured every morning before and after consuming the juice. Results: There was an average reduction of 7.4 mmHg in systolic blood pressure and 5.4 mmHg in diastolic blood pressure after 7 days of intervention, indicating a positive effect of tomato juice in lowering blood pressure. Conclusion: Daily administration of tomato juice for 7 days effectively reduced blood pressure in an elderly hypertensive individual, suggesting it as a safe and practical non-pharmacological therapy.
Abstract:Background: Diabetic ulcers are a chronic complication frequently experienced by individuals with diabetes mellitus and significantly contribute to morbidity, mortality, and lower extremity amputation rates. Effective wound…
und management is key to preventing further complications. Modern dressings based on the moist wound healing principle have been proven more effective than conventional methods, as they maintain wound moisture and support tissue regeneration. Objective: To describe the treatment of diabetic ulcers using the modern dressing method with red fruit (Pandanus conoideus Lamk) ointment in Gelang Village, Rakit District. Methods : This study used a descriptive case study approach involving one diabetic ulcer patient who met the inclusion criteria. Wound care was performed every two days for 14 days using modern dressing and red fruit ointment. Data were collected through observation, interviews, and documentation. Results: There was an improvement in wound conditions after the application of red fruit ointment, marked by an increase in granulation tissue and a decrease in necrotic tissue. The active ingredients in the ointment such as β-carotene, tocopherol, oleic acid, and linoleic acid have antioxidant and anti-inflammatory effects that accelerate the healing process. Conclusion: Modern dressing with red fruit ointment is effective in accelerating the healing process of diabetic ulcers and can serve as an alternative topical therapy to support optimal wound recovery
Abstract:Background: Type 2 diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels due to insulin resistance or impaired insulin secretion. One effort to help lower blood glucose levels is…
s through complementary therapy using natural ingredients such as tomato juice and dragon fruit juice, which contain various active compounds such as lycopene, fiber, vitamin C, and antioxidants.Objective: To determine the effect of tomato juice and dragon fruit juice on 2-hour post prandial blood glucose levels in type 2 diabetes mellitus patients. Methods: This research is a case study with two subjects who met the inclusion criteria. The intervention was administered for 7 days, during which subjects consumed tomato juice and dragon fruit juice. Blood glucose levels were measured before and after the intervention using an Easy Touch device. Results: The study showed a decrease in blood glucose levels after administration of both juices. This indicates that the combination of tomato juice and dragon fruit juice can significantly lower blood glucose levels. Conclusion: Administering tomato juice and dragon fruit juice can be an effective complementary therapy in lowering blood glucose levels in patients with type 2 diabetes mellitus.