Abstract:Handwashing with soap is one of the most effective public health measures for preventing gastrointestinal and respiratory infections among children. However, despite ongoing health education efforts, many children still…
do not perform proper handwashing techniques. Interactive educational approaches, such as demonstration methods combined with songs, may enhance children's practical skills more effectively than conventional instruction. This study aimed to determine the effect of health education using a demonstration method on handwashing with soap skills among children in the BTN AL community, Entrop Subdistrict, South Jayapura District. A quantitative study with a one-group pretest-posttest pre-experimental design was conducted involving 20 child participants selected through total sampling. The intervention consisted of a live demonstration of the WHO six-step handwashing technique accompanied by a modified version of the children's song Naik Becak. Participants' handwashing skills were assessed before and after the intervention using the WHO Standard Hand Hygiene Observation Checklist. Data were analyzed using the Wilcoxon Signed-Rank Test. The findings demonstrated a significant improvement in children's handwashing skills following the intervention. Before receiving health education, most participants were unable to perform the recommended handwashing procedure correctly. After the intervention, 18 participants (90%) successfully demonstrated all six handwashing steps independently, while only two participants (10%) still required assistance. Statistical analysis showed a significant difference between pretest and posttest scores (p < 0.001). The study concludes that health education delivered through a demonstration method combined with a modified children's song effectively improves handwashing with soap skills among children. This approach may serve as an innovative and engaging strategy for promoting healthy hygiene behaviors in early childhood.
Abstract:Penelitian ini bertujuan memberikan analisis yang mendalam mengenai konsep rukhsah atau dispensasi puasa bagi mahasiswa yang mengalami kondisi medis tertentu, dengan mengintregasikan perspektif fikih dan kebutuhan praktis…
s dalam kehidupan akademik. Dalam radisi hukum islam, rukhsah merupakan bentuk keringanan yang diberikan kepada mukallaf Ketika kondisi normal tidak memungkinkan pelaksanaan ibadah secara sempurna. Mahasiswa dengan gangguan Kesehatan seperti penyakit kronis, gangguan metabolik, masalah gastrointestinal, atau kondisi psikis yang diperparah oleh puasa, seringkali menghadapi dilema antara menjaga komitmen religious dan mempertahankan stabilitas Kesehatan. Penelitian ini menggunakan pendekatan analitis deskriptif melalui telaah literatur fikih klasik, fatwa kontemporer, serta kajian medis yang relevan guna untuk menetapkan Batasan dan indikator objektif terkait kebolehan meninggalkan atau mengganti puasa.
Hasil kajian menunjukkan bahwa fiqh al rukhsah menjadi dasar pemberian dispensasi. Syariat mengedepankan keselamatan dan menolak kemudharatan, sehingga mahasiswa yang kondisi medisnyadapat memburuk apabila berpuasa berhak mendapatkan rukhsah berupa tidak berpuasa, mengganti di hari lain, atau dalam kasus membayar fidyah. Disamping itu, penelitian menemukan bahwa Sebagian mahasiswa memahami bahwa kerangka fikih yang membolehkan keringanan sehingga mulai memahami rukhsah puasa yang dianjurkan dalam kondisi medis tertentu. Diperlukannya juga edukasi fikih Kesehatan di lingkungan kampus untuk meningkatkan literasi keagamaan dan kesehatan, sehingga mahasiswa mampu mengambil Keputusan ibadah yang tepat, seimbang, dan sesuai dengan ketentuan syariat maupun kebutuhan medis mereka.
Abstract:Background: Pregnancy is a process of fertilization between spermatozoa and ovum, followed by implantation or nidation. During the first trimester of pregnancy, pregnant women usually experience discomfort such as nausea…
and vomiting. About 50-80% of pregnant women experience nausea and vomiting in early pregnancy, typically between 6-12 weeks of gestation, due to gastrointestinal and psychological distress. One therapy to reduce the discomfort of nausea and vomiting during pregnancy is the use of citrus lemon aromatherapy. Purpose: This study aims to determine the effect of inhaling citrus lemon aromatherapy on the degree of nausea and vomiting (emesis gravidarum) in pregnant women during the first trimester. Methods: This paper uses a type of qualitative research whit a case study design. Results: The results of the nursing implementation stated that after the administration of citrus lemon aromatherapy inhalation, there was a decrease in the PUQE-24 score, namely from the category of moderate nausea and vomiting with a score of 12 to no nausea and vomiting with a score of 3. Conclusion: The effect of inhaling citrus lemon aromatherapy on the degree of nausea and vomiting (emesis gravidarum) in pregnant women during the first trimester is quite effective in helping to reduce nausea and vomiting in pregnant women.
Abstract:Antimicrobial resistance has driven the urgent need to develop new antibacterial candidates with favorable efficacy, pharmacokinetic properties, and safety profiles. Aaptamine derivatives, secondary metabolites isolated…
from marine sponges of the genus Aaptos, have demonstrated potential as drug candidates; however, studies evaluating their drug-likeness, Absorption, Distribution, Metabolism, and Excretion (ADME) properties, and toxicity profiles remain limited. This study aimed to prioritize aaptamine, demethyl(oxy)aaptamine, and isoaaptamine as potential antibacterial candidates through SwissADME and ProTox-II analyses using an in silico approach. The results demonstrated that all three compounds satisfied the Lipinski's Rule of Five criteria for drug-likeness, exhibited high gastrointestinal absorption, and achieved a bioavailability score of 0.55. All compounds were predicted to belong to toxicity class 4, with predicted LD₅₀ values of 1300 mg/kg for aaptamine, 500 mg/kg for demethyl(oxy)aaptamine, and 1350 mg/kg for isoaaptamine, while none showed hepatotoxic or cytotoxic properties. The integrated analysis indicated that isoaaptamine exhibited the most balanced drug-likeness, ADME profile, and safety characteristics, making it the highest-priority antibacterial candidate. This study concludes that the integration of SwissADME and ProTox-II provides an effective preliminary approach for screening marine natural product-derived drug candidates. The novelty of this study lies in the integrated application of drug-likeness, ADME, and toxicity analyses to systematically prioritize three aaptamine derivatives, thereby providing a more comprehensive lead compound selection strategy for antibacterial drug discovery.
Abstract:Latar Belakang: Pertumbuhan coffeeshop yang pesat di kota-kota pelajar Indonesia mendorong peningkatan konsumsi minuman berkafein di kalangan mahasiswa. Kafein diketahui dapat merangsang sekresi asam lambung dan melemahkan…
an sfingter esofagus bawah sehingga berpotensi menimbulkan gangguan gastrointestinal. Tujuan: Menganalisis hubungan antara pola konsumsi minuman berkafein dengan kejadian gangguan gastrointestinal pada mahasiswa di Kota Jember. Metode: Penelitian cross-sectional dengan 150 mahasiswa di Kota Jember yang dipilih melalui purposive sampling. Data dikumpulkan menggunakan kuesioner Likert yang telah diuji validitas dan reliabilitasnya. Analisis data meliputi uji korelasi Spearman dan regresi logistik biner. Hasil: Mayoritas responden memiliki pola konsumsi kafein kategori sedang (89,3%) dan mengalami gangguan gastrointestinal kategori sedang (62,7%). Terdapat hubungan positif signifikan antara pola konsumsi kafein dengan kejadian gangguan gastrointestinal (r = 0,434; p < 0,001). Analisis multivariat menunjukkan pola konsumsi kafein (OR = 1,139; 95% CI: 1,063–1,220) dan riwayat penyakit lambung (OR = 9,354; 95% CI: 2,821–31,022) sebagai prediktor independen yang signifikan. Simpulan: Pola konsumsi minuman berkafein berhubungan secara positif dan signifikan dengan kejadian gangguan gastrointestinal pada mahasiswa di Kota Jember. Mahasiswa dengan riwayat penyakit lambung memiliki risiko hampir sembilan kali lebih besar mengalami gangguan gastrointestinal sedang-berat.