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Showing 29 articles found for "Systemic"

ASSOCIATION BETWEEN INHALED CORTICOSTEROIDS AND OSTEOPOROSIS: A REVIEW

Nurfadilasari, Ulfa Mustofa, Liberitera, Sternatami
Abstract: Inhaled corticosteroids (ICS) are commonly prescribed to manage asthma and chronic obstructive pulmonary disease (COPD) due to their local anti-inflammatory effects in the airways. However, prolonged or high-dose ICS use… has been associated with systemic adverse effects, including decreased bone mineral density (BMD) and increased risk of osteoporosis. This review aimed to examine the association between ICS use and the risk of osteoporosis or fractures, and to identify modifying factors such as dose, duration, patient age, sex, and type of corticosteroid used. Literature review was conducted using databases including PubMed, Scopus, and Web of Science. Articles were selected using specific inclusion and exclusion criteria. The review focused on original studies published up to March 2025, resulting in 28 relevant articles, of which 6–8 high-quality studies were analyzed in depth. Most studies demonstrated that long-term or high-dose ICS use is associated with decreased BMD and increased risk of fractures, especially in elderly COPD patients. The greatest risk was linked to fluticasone and budesonide at doses ≥500 µg/day. Some studies found neutral or even protective effects in specific subgroups, indicating population-dependent variability. Meta-analyses revealed conflicting results due to heterogeneity in populations and methodologies. High-dose and long-term ICS use may increase the risk of osteoporosis. Clinicians should consider individualized risk assessments and adopt strategies such as using the lowest effective dose, monitoring BMD, and providing calcium and vitamin D supplementation in at-risk populations.

THE LEGAL POLITICS OF THE FORMATION OF JOB CREATION LAW WITHIN THE FRAMEWORK OF RESPONSIVE LAWS

Febriana, Lega Rahayu, Setiadi , Wicipto, Ahsin Thohari, Ahmad
Abstract: The introduction of the omnibus methodology to Indonesian lawmaking through the Job Creation Law has generated intense scholarly debate over the balance between regulatory efficiency and democratic legitimacy. Drawing on… Nonet and Selznick’s responsive law theory, this study examines the legal politics underpinning the formation of Law No. 11 of 2020, PERPPU No. 2 of 2022, and Law No. 6 of 2023 within Indonesia’s civil‐law framework. Using normative legal research methods including statutory interpretation, constitutional doctrinal analysis, and comparative legal study this article traces the procedural trajectory from initial draft to successive judicial reviews (Decision Nos. 91/PUU-XVIII/2020 and 168/PUU-XXI/2023). The findings reveal systemic procedural deficiencies: exclusion of affected stakeholders, lack of meaningful public participation, and executive reliance on emergency powers instead of mandated legislative revision. The Constitutional Court’s interventions have served as corrective “strange attractors,” introducing “meaningful participation” requirements (right to be heard, right to be considered, and right to explanation) and compelling the government to adopt legislative reforms. However, persistent executive resistance underscores enduring tensions between efficiency‐oriented omnibus reforms and procedural legitimacy. The study concludes that forthcoming legislative efforts particularly the mandated separate Employment Law will determine whether Indonesia’s legal system advances toward genuinely responsive law or reverts to repressive practices. These insights hold broader significance for comparative constitutionalism and the global discourse on omnibus legislation in developing democracies.

MITIGATING EMERGENCY RISKS IN SUNNAH CUPPING THROUGH MEDICAL AND SHARIA INTEGRATION

Isdianto, Andik, Fitrianti, Novariza, Arif , Abdul Hamid, Widada , Wahyudi
Abstract: Sunnah cupping therapy is a traditional Islamic health practice increasingly embraced for its spiritual and therapeutic benefits. However, its widespread use, especially by uncertified practitioners, raises serious concerns… rns about patient safety and emergency risks. This study aims to identify key systemic risk factors of medical emergencies related to sunnah cupping and propose an integrative framework combining Islamic jurisprudence (fiqh) with modern clinical standards. A qualitative descriptive approach was employed using a systematic literature review of peer-reviewed journals, clinical reports, Islamic texts, and contemporary fatwas. Thematic analysis revealed five major risk categories: lack of medical screening, unlicensed practitioners, hidden comorbidities, absence of emergency protocols, and poor understanding of medical safety. Reported complications included hypovolemic shock, infections, and prolonged wound healing—especially in patients with undiagnosed diabetes or coagulation disorders. The study also found that public misconceptions equating religious merit with clinical safety further worsen these risks. The research highlights the urgent need for standardized medical and sharia-based training, certification systems, and public education. Collaboration among healthcare professionals, Islamic scholars, and educational institutions is essential to establish a safe, accountable, and spiritually valid model of sunnah cupping. Integrating medical protocols with fiqh compliance can significantly reduce emergency incidents, enhance practitioner competency, and preserve the prophetic nature of the practice within a modern health framework. These findings offer a strategic path for safer implementation of prophetic medicine across Muslim communities.

THE IMPORTANCE OF FASTING IN CELL REGENERATION: A SCIENTIFIC AND ISLAMIC PERSPECTIVE

Isdianto, Andik, Al Indunissy, Nuruddin, Fitrianti, Novariza, Arif, Abdul Hamid, Widada, Wahyudi
Abstract: Fasting is a religious practice that not only holds spiritual significance in Islamic teachings but also contributes substantially to the body's physiological repair. This study aims to examine the relationship between Islamic… slamic fasting—particularly Ramadan and sunnah fasting—and cellular repair processes through biological mechanisms such as autophagy, cell regeneration, and mitochondrial function enhancement. Using an integrative literature review method, this study synthesized findings from scientific and Islamic sources retrieved from databases including PubMed, Scopus, ScienceDirect, and Google Scholar from 2015 to 2025. The findings reveal that fasting positively affects systemic inflammation reduction, improved insulin sensitivity, metabolic regulation, and the prevention of premature aging and degenerative diseases. Moreover, fasting strengthens psychological and spiritual dimensions, supporting mental health and enhancing emotional resilience. This synergy between biological and spiritual benefits highlights fasting as a holistic health strategy. The study affirms that Islamic values align with modern preventive health principles and offer a solid foundation for spiritually based health promotion. Further research is recommended to evaluate specific biomarkers related to fasting-induced cell regeneration.

MEDICAL EMERGENCIES IN SUNNAH CUPPING THERAPY: A CLINICAL REVIEW AND ISLAMIC ETHICAL PERSPECTIVE

Isdianto, Andik, Fitrianti, Novariza
Abstract: Sunnah cupping therapy is widely recognized as part of prophetic medicine with spiritual and therapeutic benefits. However, its implementation often overlooks potential medical emergencies, especially when conducted without… out proper safety protocols. This study aims to identify types of medical emergencies associated with sunnah cupping therapy through a critical literature review. A descriptive-qualitative approach was used, based on a systematic review of scientific publications from 2010 to 2024 obtained from databases such as PubMed, ScienceDirect, and Google Scholar. The results revealed seven major types of complications in cupping practice: infections (local to systemic), severe bleeding and hematoma, vasovagal and hypovolemic shock, allergic reactions, burns (in fire cupping), neurological responses (epilepsy), and dissociative psychological responses (possession). These complications are primarily caused by the lack of medical screening, limited practitioner training, and absence of emergency handling protocols. The study emphasizes the urgency of integrating Islamic ethical values with emergency medical standards in cupping practice. It recommends enhancing public education, practitioner certification, and clinical regulations to ensure patient safety.

THE IMPACT OF MENTAL HEALTH DISORDERS ON PHYSICAL DISEASE RISKS: A COMPREHENSIVE REVIEW

Isdianto, Andik, Al Indunissy, Nuruddin, Fitrianti , Novariza
Abstract: This study evaluates the impact of mental health disorders such as stress, anxiety, and depression on the risk of various physical illnesses, including cardiovascular diseases, type 2 diabetes, obesity, immune system disorders,… orders, respiratory conditions, skin disorders, digestive ailments, and osteoporosis. Employing a literature review methodology, the research analyzed data from previous studies, uncovering that mental disorders elevate the risk of cardiovascular diseases through oxidative stress and systemic inflammation mechanisms. The link between stress and glycemic dysregulation in type 2 diabetes highlights a trend towards increased insulin resistance. Depression, closely associated with obesity, is often exacerbated by unhealthy eating habits used as coping mechanisms. Chronic stress-induced immune system disorders result in decreased immune responses, while respiratory issues such as asthma are intensified by increased anxiety. Skin conditions like psoriasis and eczema frequently worsen due to psychological stress. In digestive disorders such as irritable bowel syndrome, stress contributes to more severe symptoms, and osteoporosis is similarly affected by chronic stress impacting bone metabolism. These findings affirm the critical importance of routine mental health screenings and the integration of effective public health interventions in overall health management, as exemplified by the Rehab Hati Foundation. Public health programs that enhance mental health can aid in preventing and managing physical illnesses, improving life quality, and reducing overall health burdens. The conclusion highlights the essential role of effective mental health management as both a preventive and therapeutic strategy.

Pendekatan TEACCH dalam Meningkatkan Kemandirian Belajar Anak dengan ASD: Tinjauan Literatur Sistematis

Lukmanul Hakim, Muh. Hasani, Muh. Rusli Umaini
Abstract: Individuals with Autism Spectrum Disorder (ASD) commonly face challenges in independent learning and mastery of functional skills due to deficits in communication, social interaction, as well as repetitive and restricted… behaviors. The Treatment and Education of Autistic and Related Communication Handicapped Children (TEACCH) approach was developed to address the specific educational needs of this population through structured, visually based, and strengths-based learning. Although the effectiveness of TEACCH has been widely reported globally, studies systematically examining its application within the Indonesian educational context remain limited. This study aims to critically evaluate the effectiveness of the TEACCH approach in enhancing independent learning among children with ASD in Indonesia. Using a systematic review method based on the PRISMA protocol, 15 scholarly articles published between 2017 and 2024 were thematically analyzed to identify TEACCH’s contribution to increasing independence in academic contexts and activities of daily living (ADL). The analysis revealed that TEACCH implementation consistently enhances children’s independence, as indicated by significant improvements in academic task completion (with an average score increase of 34–50 points), as well as improvements in ADL skills such as dressing, eating, and maintaining personal hygiene. The success of this approach is determined by the integration of structural elements, such as environmental organization, the use of visual aids, consistent routines, and collaboration between teachers and parents. This study concludes that TEACCH is an adaptive, effective, and relevant approach for implementation within the Indonesian education system. The novelty of this research lies in its contextual focus on TEACCH application in Indonesia, as well as strategic recommendations for its integration into special education (SLB) and inclusive school curricula through systemic educator capacity-building.

Penerapan Pembelajaran Project Based Learning untuk Meningkatkan Kemampuan Berkomunikasi Peserta Didik SMP dalam Pembelajaran di Kelas

Herisa Sintia, Desy Safitri, Sujarwo
Abstract: This study aims to examine the effectiveness of the Project Based Learning (PjBL) model in enhancing the communication skills of junior high school students through a literature review approach. The study critically analyzes… yzes a range of scholarly literature and recent research findings concerning the implementation of PjBL, particularly in the context of developing oral, written, and interpersonal communication skills within primary education settings. The findings indicate that PjBL fosters an active, collaborative, and contextual learning environment that significantly contributes to the improvement of students’ communication abilities. Through project completion that involves exploration, presentation, and group interaction, learners are encouraged to articulate ideas effectively, engage in active listening, and produce writing with logical and argumentative structure. Moreover, the model has been shown to enhance students' self-confidence, independence, and sense of responsibility toward their own learning process. Nonetheless, the implementation of PjBL continues to face several challenges, including limited instructional time, insufficient teacher understanding of meaningful project design, and inadequate supporting resources. Without systemic support and continuous professional development for educators, the application of this model risks becoming a mere formality with little substantive impact. Therefore, this study recommends further empirical research using a mixed-methods approach to investigate the effectiveness of PjBL across various subjects and educational levels. Such studies are expected to strengthen the theoretical foundation and promote the adoption of PjBL as a transformative learning strategy in shaping learners.

Akar Radikalisme di Ruang Kelas: Eksplorasi Faktor Pemicu di Lembaga Pendidikan Islam

Zainuddin, Erik Pebrikarlepi, Ulfa Hoyriah, Siti Murtosiah
Abstract: Radicalism poses a significant threat to social cohesion and national unity in Indonesia. This research explores the strategic role of education in preventing the spread of radical ideologies and building a tolerant society.… ety. The primary focus is analyzing the systemic design of education to promote contextual and inclusive religious values. Employing a qualitative-descriptive approach, the study investigates how curriculum, pedagogy, and teacher roles can shape religious narratives supporting peace and humanity. The research reveals that rigid and doctrinal religious education potentially triggers radicalization, while dialogical and contextual approaches can effectively counter the spread of extremist ideologies. Key findings underscore the need for transforming religious education by emphasizing deep understanding of tolerance, conflict resolution, and diversity. The primary contribution of the research is a model of educational approach integrating progressive religious interpretations with universal humanitarian values. The study's implications include educational policy recommendations that can strengthen social capital and prevent radicalization among Indonesian youth.

Efektivitas Bible Camp terhadap Pembinaan Iman Kristen para Pemuda

Yerliani Boymau, Hendrik A. E. Lao
Abstract: Youth represent a socio-psycho-spiritual entity undergoing a critical transitional phase, characterized by identity crises, value disorientation, and pressures from secular-cultural influences. Within the framework of Christian… ristian pastoral theology and pedagogy, faith formation serves as a strategic mechanism to cultivate integrative spiritual maturity, encompassing cognitive (doctrinal understanding), affective (spiritual affection), and conative (practical orientation) dimensions. This study analyzes the effectiveness of Bible Camp as an experiential learning-based faith formation model in the spiritual development of youth. Employing a qualitative descriptive approach through participatory observation, in-depth interviews, and document analysis, the research explores the contribution of Bible Camp to the internalization of theological values, the construction of religious identity, and the strengthening of faith community cohesion. The findings indicate that Bible Camp activities—such as hermeneutic study, collective worship, existential reflection, and group dynamics—result in significant faith transformation on both personal and communal levels. This process aligns with Streib’s faith development theory and Mezirow’s transformative learning theory, which emphasize cognitive reconstruction through reflective experience within a social context. Bible Camp effectively mediates the transition from conventional faith to reflective and dialogical faith, while enhancing youth’s spiritual competencies in confronting the complexities of contemporary reality. The findings reinforce the assumption that faith formation in interactive non-formal settings is more effective than conventional instructional approaches in producing theological and ethical paradigm shifts. Therefore, Bible Camp is positioned as a relevant and contextual ecclesiological instrument in the recontextualization of Christian faith education. This model functions not only as a venue for individual spiritualization but also as a catalyst for the formation of resilient, participatory, and transformative Christian character within a pluralistic socio-religious ecosystem. Recommendations are directed towards institutionalizing Bible Camp as a systemic strategy for youth faith formation in the mission of the contemporary church.